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. 2022 Feb 28;12(3):151. doi: 10.3390/bios12030151

Table 3.

Performance of the latest biosensors for SARS-CoV-2 detection reported in literature.

Biosensor Type Target Analyte Sample LoD
(Copies/mL)
Detection Time Number of Samples Per Test Operation Ref.
Electrochemical ORF1ab Throat/oral swabs, sputum, urine, plasma, feces 200 ~3 h Single By hand [3]
Electrochemical N gene Nasopharyngeal/
oropharyngeal swabs
2.58 × 105 15 min Single By hand [4]
Electrochemical N and S genes Nasopharyngeal swab 1000 <2 h Single By hand [5]
Graphene-based FET S protein Nasopharyngeal swab 242 ~120 s Single By hand [7]
LSPR-microcavity Pseudovirus Artificial saliva 319 <30 min Up to 100 samples Automated This work

FET: field-effect transistor; ORF1ab: open reading frame 1ab; LoD: limit of detection; Ref.: Reference.