Table 8.
Types of stem cells used in studies on management of primary knee osteoarthritis with stem cells that were identified during an evidence-based, systematic review of the literature according to the PRISMA guidelines [198] performed on 7 August 2021.
| Cell Type | Nall | NpkOA | Description |
|---|---|---|---|
| ADRCs | 36 | 35 | Adipose-derived regenerative cells |
| ADSCs | 22 | 18 | Adipose-derived stem cells (obtained by culturing ADRCs) |
| MFF | 21 | 21 | Micro-fragmented fat (from liposuction) |
| CLL | 1 | 1 | Centrifuged liposuction liquid |
| BMA | 1 | 1 | Bone marrow aspirate |
| BMAC | 38 | 26 | Bone marrow aspirate concentrate |
| BM-MSCs | 34 | 25 | Bone-marrow-derived mesenchymal stem cells |
| Cs/CPs | 2 | 0 | Chondrocytes and chondrocyte precursors |
| CSCs | 1 | 0 | Cartilage stem cells |
| MACI | 1 | 0 | Matrix-induced, autologous chondrocyte implant |
| S-MSCs | 4 | 1 | Matrix-induced MSCs from synovia |
| Ch-TGFβ | 2 | 2 | Chondrocytes that overexpress transforming growth factor beta |
| hUC-MSCs | 4 | 3 | Human-umbilical-cord-derived MSCs |
| hUCB-MSCs | 7 | 6 | Human-umbilical-cord-blood-derived MSCs |
| P-MSCs | 1 | 1 | Placental MSCs |
| pBSCs | 8 | 4 | Activated peripheral blood stem cells |
| Sum | 183 | 143 |