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. 2022 Mar 11;11(6):965. doi: 10.3390/cells11060965

Table 11.

Reported outcome in studies on treatment of primary knee osteoarthritis with autologous, adipose-derived regenerative cells, or autologous, adipose-derived stem cells listed in Table 10.

R FA Reported Outcome
Autologous ADRCs
[19] Garza
  • WOMAC total score at BL and at W6, M3, M6 and M12 (mean, median, interquartile range, median percentage range, minimum, maximum)

  • Cartilage loss (mean at BL, mean change at M6)

  • Outerbridge classification (median at BL, range at BL, median change at M6)

[52] Koh
  • VAS pain score (mean and SD at baseline and at last follow-up)

  • KOOS sub-scores (mean improvement from BL to LFU)

  • Lysholm score (mean and SD at BL and LFU)

  • Weight-bearing line (%) (mean and SD at BL and LFU)

  • Femorotibial angle (°) (mean and SD at BL and LFU)

Autologous ADSCs
[18] Lee
  • VAS pain score at BL, M3 and M6 (mean)

  • WOMAC total and sub-scores at BL, M3 and M6 (mean)

  • KOOS sub-scores at BL, M3 and M6 (mean)

  • Size of cartilage defect in MRI at BL and M6 (mean, SD)

[30] Freitag
  • VAS pain score at BL, M1,5, M3, M6 and M12 (mean, 95% CI)

  • KOOS sub-scores at BL, M1,5, M3, M6 and M12 (mean, 95% CI)

  • WOMAC score at BL, M1,5, M3, M6 and M12 (mean, 95% CI)

[56] Zhang
  • VAS pain score at BL, M3, M6, M12, M24 and M36 (mean, SD)

  • WOMAC total score at BL, M3, M6, M12, M24 and M36 (mean, SD)

[60] Qiao
  • SF-36 Physical Component and Mental Component sub-scores at BL, M3, M6, M9, M12 and M24 (mean, SD)

Abbreviations: ADRCs, adipose-derived regenerative cells; ADSCs, adipose-derived stem cells; R, reference; FA, first author; BL, baseline; W6, 6 weeks post treatment; M3/M6/M9/M12/M24, three/six/nine/twelve/24 months post-treatment; LFU, last follow-up (range, M14–M24; mean: M19.8); SD, standard deviation; and CI, confidence interval.