Table 1.
Demographic characteristics at admission of patients infected with COVID-19.
| Total n = 61 (100) Number and Percentage |
Moderate n = 34 (56) Number and Percentage |
Severe n = 27 (44) Number and Percentage |
p | |
|---|---|---|---|---|
| Women | 17 (28) | 11 (32) | 6 (22) | NS |
| Men | 44 (72) | 23 (68) | 21 (78) | NS |
| Age | 56 ± 13 | 54 ± 12 | 59 ± 14 | NS |
| BMI (kg/m2) | 29 ± 4 | 29 ± 4 | 29 ± 4 | NS |
| Temperature (°C) | 36.6 ± 0.46 | 36.5 ± 0.43 | 36.7 ± 0.49 | NS |
| Laboratory at the admission Median (Min–Max) range | ||||
| PAO2 (58.5–67.1 mmHg) | 66.9 (34–223) | 67 (34–223) | 66.4 (62–93) | NS |
| PCO2 (30.4–40 mmHg) | 31.7 (12.2–81.2) | 32 (12.2–81.2) | 31.6 (22–71) | NS |
| PAO2/FIO2 (>164) | 128 (26.8–299) | 145 (26.8–281) | 113 (30–299) | NS |
| SpO2/FIO2 (>300) | 138 (50–280) | 157 (88–240) | 128 (50–280) | 0.007 |
| Urea (<40 mg/dL) | 16 (5.6–106.7) | 29.2 (16–60) | 30 (13–224) | NS |
| Creatinine (mg/dL) | 0.90 (0.5–5.3) | 1 (0.5–2.5) | 0.8 (0.5–5.3) | NS |
| Ureic Nitrogen (7–25 mg/L) | 16 (5.6–196-7) | 15.7 (7.5–36) | 17 (5.6–106.7) | NS |
| TC (<200 mg/dL) | 136 (69–217) | 140 (69–217) | 132 (86–190) | NS |
| HDL (mg/dL) | 31 (14–60) | 32 (14–60) | 31 (14–45) | NS |
| LDL (mg/dL) | 70 (28–140) | 64 (35–135) | 79 (28–140) | NS |
| DHL (mg/dL) | 253 (124–515) | 233 (128–412) | 255 (124–515) | NS |
| TB (mg/dL) | 0.60 (0.12–4.10) | 0.50 (0.12–1.3) | 0.70 (0.33–4.10) | 0.02 |
| DB (mg/dL) | 0.20 (0.10–1.20) | 0.20 (0.10–1.2) | 0.20 (0.10–0.8) | NS |
| TG (<150 mg/dL) | 133 (62–726) | 137 (62–726) | 133 (77–328) | NS |
| Leukocytes (3.5–10.3 × 103/µL) | 8.8 (2–25) | 8.2 (2–14) | 11.5 (3–25) | 0.003 |
| Lymphocytes (0.99–3.2 × 103/µL) | 0.8 (0.14–9.6) | 0.92 (0.42–9.6) | 0.69 (0.14–8.2) | 0.01 |
| Platelets (150,000–500,000 × 103/µL) | 244 (16–576) | 226 (16–576) | 254 (122–412) | 0.057 |
| Ferritin (11–307 ng/mL) | 541 (147–2592) | 513 (147–2100) | 592 (175–2592) | NS |
| IL-6 (pg/mL9) | 67 (7.8–638.5) | 30.2 (7.8–304) | 94 (7.8–639) | 0.003 |
| Index N/L | 11.5 (1–89) | 10 (3–89) | 13 (1–83) | NS |
| D-Dimer (0–24 µg/mL) | 700 (136–16440) | 615 (136–5130) | 810 (210–16,640) | 0.08 |
| CRP (1–3 mg/L) | 146 (20–2450) | 280 (20–1380) | 146 (32–2450) | NS |
| Comorbidities (%) | ||||
| DM | 6 (10) | 4 (7) | 2 (3) | NS |
| SAH | 5 (8) | 3 (5) | 2 (3) | NS |
| Dyslipidemia | 11 (18) | 8 (13) | 3 (5) | NS |
| DM + Dyslipidemia | 5 (8) | 2 (3) | 3 (5) | NS |
| DM + SAH | 5 (8) | 2 (3) | 3 (5) | NS |
| SAH + Dyslipidemia | 3 (5) | 0 | 2 (5) | NS |
| SM | 9 (15) | 6 (10) | 3 (5) | NS |
| Healthy Subjects without comorbidities | 17 (28) | 8 (13) | 9 (15) | NS |
| Normal weight | 13 (21) | 6 (18) | 7 (26) | NS |
| Overweight | 24 (39) | 17 (50) | 7 (26) | 0.06 |
| Obesity | 24 (39) | 11 (33) | 13 (48) | NS |
| COPD | 1 (1.6) | 0 | 1 (4) | NS |
| ECKD | 2 (3.3) | 0 | 2 (8) | NS |
| Norepinephrine | 18 (29) | 1 (3) | 17 (63) | 0.0001 |
| Enteral nutrition | 26 (43) | 22 (65) | 4 (15) | 0.001 |
| Deaths | 1 (1.6) | 0 | 1 (4) | NS |
Abbreviations: BMI = Body mass index, HR = Heart rate, MAP = Mean arterial pressure, HDL = High-density lipoproteins, LDL = Low-density lipoproteins, TB = Total bilirubin, DB = Direct bilirubin, IL = Interleukin, N/L = neutrophil&/lymphocyte, DM = Diabetes mellitus, SAH = Systemic arterial hypertension, CD = Cardiovascular disease, COPD = Chronic obstructive pulmonary disease, ECKD = End-stage chronic kidney disease. FiO2 = inspired fraction of oxygen, PAO2 = Blood pressure oxygen, PCO2 = Partial pressure carbon dioxide, SpO2 = Arterial oxygen saturation, ECKD = End-stage chronic kidney disease, TC = Total cholesterol, TG = Triglycerides, MS = Metabolic syndrome.