FIG. 3.

Mean (SEM) LTB₄ levels in cell-free BAL fluid of mice infected with 3.5 × 10⁷ CFU of S. pneumoniae. Animals that were sacrificed at 12 h had received a single injection of L-NMMA (3 mg/kg) at time zero, while animals sacrificed at 24 h had received a second injection 12 h postinfection. Comparisons indicated by the asterisks (∗∗, P < 0.01, and ∗∗∗, P < 0.001) were made between infected animals and their respective uninfected controls (infected versus control and infected plus L-NMMA versus L-NMMA).