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Multivariate analysis for progression-free interval. Multivariate Cox regression of the 8-gene signature with clinical variables. Significance levels are annotated. Clinical factors such as gleason score, psa level, tumor TNM stage, and age at diagnosis were considered as confounding variables in the analysis. Both hazard ratios and 95% confidence intervals were shown in the forest plot and factors reached a significant level were plotted in red. *** p-value < 0.001.
