Okimoto 2009.
Methods | Prospective, randomised trial. | |
Participants | 50 elderly patients (mean age 80 years; 60% male) with community‐acquired pneumonia. | |
Interventions | Meropenem 500 mg i.v. q12h vs meropenem 1.0 g/day i.v. continuous 24 h infusion; mean treatment duration 12 to 13 days. | |
Outcomes | Clinical efficacy. Bacteriological efficacy. |
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Notes | Able to obtain only partial translation of this trial from Japanese into English. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomly assigned, but unclear randomisation method. |
Allocation concealment (selection bias) | Unclear risk | Unclear, complete translation not available. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Unclear, complete translation not available. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All patients assessed for clinical cure, but not for bacteriological efficacy. |
Selective reporting (reporting bias) | Unclear risk | Unclear; complete translation not available. |
Other bias | Unclear risk | Unclear; complete translation not available. |