Cousson 2010.
Trial name or title | Comparison of pharmacodynamic interest of ceftazidime continuous infusion vs intermittent bolus administration in epithelial lining fluid concentrations of patients with severe nosocomial pneumonia |
Methods | Prospective, randomised trial |
Participants | Enrolment = 32, critically ill patients |
Interventions | Ceftazidime 20 mg/kg i.v. bolus, then 60 mg/kg/24 h continuous infusion vs ceftazidime 20 mg/kg i.v. over 30 minutes q8h (combined with tobramycin 5 mg/kg i.v in both groups) |
Outcomes | Ceftazidime epithelial lining fluid concentrations MIC for causative organisms |
Starting date | Not stated |
Contact information | Joel Cousson (jcousson@chu‐reims.fr) |
Notes | Data not published, information obtained from poster presentation |