Table 4.
MRI findings and their distribution in DMG and midGBM-H3wt cohorts, including correlation analysis data.
| Imaging Features | DMG n (%) | midGBM-H3wt n (%) | p-Value | |
|---|---|---|---|---|
| Location | thalamus | 15/39 (38) | 12/18 (67) | 0.086 |
| brainstem | 23/39 (59) | 6/18 (33) | 0.092 | |
| cerebellum | 1/39 (3) | 0/18 | 0.536 | |
| Edema present | 3/39 (8) | 14/18 (78) | <0.001 | |
| Rim enhancement | 17/39 (44) | 12/18 (67) | 0.155 | |
| Tumor necrosis | 24/39 (62) | 16/18 (89) | 0.060 | |
| Strong enhancement | 15/39 (38) | 10/18 (56) | 0.262 | |
| Low enhancement | 15/39 (38) | 3/18 (17) | 0.132 | |
| Mass effect | 39/39 (100) | 18/18 (100) | ||
| Multifocal lesions | 2/39 (5%) | 3/18 (17) | 0.312 | |
| Intracranial metastasis | 2/39 (5%) | 0/18 | 1.000 | |
DMG: diffuse midline glioma, H3 K27M-mutant; midGBM-H3wt: glioblastoma of the midline structures, H3 K27M-wildtype. Significant values are shown in bold.