Skip to main content
. 2022 Feb 28;12(3):325. doi: 10.3390/brainsci12030325

Figure 5.

Figure 5

Syn II expression rescues the epileptic phenotype observed in Syn2 KO animals. (A) Seizure activity as a function of age for WT (black), Syn 2 KO (red), and AAV1.hSyn.Syn2-Turbo-GFP-injected Syn2 KO rescue (blue). The rescue is almost complete at P15 and it weakens as the postnatal age increases. (B) Seizure activity at P15 including mock-injected GFP controls (AAV1.hSyn.Turbo-GFP-injected Syn2 KO). n = 9 for each group. * p < 0.05, ** p < 0.01, and *** p < 0.001 per ANCOVA followed by Tukey’s test (injected versus Syn2 KO).