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. 2022 Mar 2;12(3):342. doi: 10.3390/brainsci12030342

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Effect of purmorphamine on frequency of checking in 8-OH OCD. Statistical analysis followed by two-way ANOVA (post-hoc Bonferroni’s test). Values expressed as mean ± SEM (n = 6 rats per group). (b) Effect of purmorphamine on length of check in 8-OH OCD. Statistical analysis followed by two-way ANOVA (post-hoc Bonferroni’s test). (c) Effect of purmorphamine on recurrence time of checking in 8-OH OCD. Statistical analysis followed by two-way ANOVA (post-hoc Bonferroni’s test). (d) Effect of purmorphamine on number of stops before returning to key locale in 8-OH OCD. Statistical analysis followed by two-way ANOVA (post-hoc Bonferroni’s test). * p < 0.01 v/s vehicle control, sham control and PUR10 per se; # p < 0.01 v/s 8-OH-DPAT; #$ p < 0.01 v/s 8-OH-DPAT + PUR5; #β p < 0.01 v/s 8-OH-DPAT + PUR5 and 8-OH-DPAT + PUR10; #@ p < 0.01 v/s 8-OH-DPAT + FLX10.