. 2022 Mar 2;12(3):342. doi: 10.3390/brainsci12030342

Table 5.

Effect of purmorphamine on oxidative-stress-marker levels in 8-OH OCD.

S.no.	Groups	Oxidative-Stress Markers
S.no.	Groups	AChE (µM/mg Protein)	LDH (µM/mg Protein)	SOD (µM/mg Protein)	GSH (µM/mg Protein)	Nitrite (µM/mg Protein)	MDA (nM/mg Protein)
1.	Vehicle control	24.12 ± 0.133	117.70 ± 0.366	478.00 ± 0.684	36.51 ± 0.320	7.72 ± 0.216	35.39 ± 0.240
2.	Sham control	24.26 ± 0.208	117.20 ± 0.222	478.40 ± 0.546	36.64 ± 0.329	8.07 ± 0.186	36.20 ± 0.342
3.	PUR10 per se	24.42 ± 0.194	117.90 ± 0.329	478.20 ± 0.660	36.54 ± 0.352	7.91 ± 0.295	35.75 ± 0.418
4.	8-OH-DPAT	54.44 ± 0.354 *	401.90 ± 0.851 *	305.30 ± 0.646 *	11.61 ± 0.286 *	14.18 ± 0.259 *	76.24 ± 0.269 *
5.	8-OH-DPAT + PUR5	46.46 ± 0.337 ^#	315.40 ± 1.042 ^#	332.60 ± 0.595 ^#	16.20 ± 0.171 ^#	12.44 ± 0.169 ^#	66.64 ± 0.362 ^#
6.	8-OH-DPAT + PUR10	40.94 ± 0.226 ^#$	275.70 ± 1.046 ^#$	369.20 ± 0.460 ^#$	22.71 ± 0.342 ^#$	11.40 ± 0.091 ^#$	59.21 ± 0.383 ^#$
7.	8-OH-DPAT + FLX10	35.83 ± 0.444 ^#β	195.80 ± 1.011 ^#β	411.40 ± 0.642 ^#β	28.11 ± 0.150 ^#β	10.45 ± 0.131 ^#β	51.38 ± 0.383 ^#β
8.	8-OH-DPAT + PUR10 + FLX10	30.05 ± 0.212 ^#@	145.30 ± 1.374 ^#@	446.30 ± 0.534 ^#@	32.45 ± 0.226 ^#@	9.47 ± 0.092 ^#@	43.55 ± 0.370 ^#@

Statistical analysis followed by one-way ANOVA (post-hoc Tukey’s test). Values expressed as mean ± SEM (n = 6 rats per group). * p < 0.01 v/s vehicle control, sham control and PUR10 per se; ^# p < 0.01 v/s 8-OH-DPAT; ^#$ p < 0.01 v/s 8-OH-DPAT + PUR5; ^#β p < 0.01 v/s 8-OH-DPAT + PUR5 and 8-OH-DPAT + PUR10; ^#@ p < 0.01 v/s 8-OH-DPAT + FLX10.