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Functional interaction networks analyzed by the String Cytoscape plug-in. (A) PPI network of genes related to GABAergic synapse pathway (red), retrograde endocannabinoid signaling (green), morphine (blue) and nicotine (orange). (B) In addiction, PRKACB (red), PRKCB (orange) and GABRA1 (yellow) found the top hub genes based on the MCC algorithm.
