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. 2022 Mar 24;17(3):e0265738. doi: 10.1371/journal.pone.0265738

Table 1. Distribution of rs17004038 in patients with schizophrenia and controls in this study.

Genotype Allele
n HWE C/C C/A A/A P-valuea C A MAF P-valueb Odds ratio (95% CI) Power
Overall
    SCZ 1758 1.00 1677 80 1 0.0467 3434 82 0.0233 0.0424 1.445 (1.011–2.065) 0.520
    CTL 1507 0.012 1461 43 3 2965 49 0.0163
Male
    SCZ 946 0.77 904 41 1 0.389 1849 43 0.0227 0.368 1.250 (0.769–2.032) 0.141
    CTL 739 0.0025 715 21 3 1451 27 0.0183
Female
    SCZ 812 1.00 773 39 0 0.0456 1585 39 0.0240 0.0478 1.693 (0.999–2.869) 0.509
    CTL 768 1.00 746 22 0 1514 22 0.0143

CI, Confidence interval; CTL, control; HWE, Hardy-Weinberg equilibrium; MAF, minor allele frequency; SCZ, schizophrenia.

Boldface type indicates statistical significance.

a Genotypic p-values were calculated with Cochran-Armitage trend test.

b Allelic p-values were calculated with the χ2 test.