Table 1. Distribution of rs17004038 in patients with schizophrenia and controls in this study.
Genotype | Allele | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | HWE | C/C | C/A | A/A | P-valuea | C | A | MAF | P-valueb | Odds ratio (95% CI) | Power | |
Overall | ||||||||||||
SCZ | 1758 | 1.00 | 1677 | 80 | 1 | 0.0467 | 3434 | 82 | 0.0233 | 0.0424 | 1.445 (1.011–2.065) | 0.520 |
CTL | 1507 | 0.012 | 1461 | 43 | 3 | 2965 | 49 | 0.0163 | ||||
Male | ||||||||||||
SCZ | 946 | 0.77 | 904 | 41 | 1 | 0.389 | 1849 | 43 | 0.0227 | 0.368 | 1.250 (0.769–2.032) | 0.141 |
CTL | 739 | 0.0025 | 715 | 21 | 3 | 1451 | 27 | 0.0183 | ||||
Female | ||||||||||||
SCZ | 812 | 1.00 | 773 | 39 | 0 | 0.0456 | 1585 | 39 | 0.0240 | 0.0478 | 1.693 (0.999–2.869) | 0.509 |
CTL | 768 | 1.00 | 746 | 22 | 0 | 1514 | 22 | 0.0143 |
CI, Confidence interval; CTL, control; HWE, Hardy-Weinberg equilibrium; MAF, minor allele frequency; SCZ, schizophrenia.
Boldface type indicates statistical significance.
a Genotypic p-values were calculated with Cochran-Armitage trend test.
b Allelic p-values were calculated with the χ2 test.