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. 2022 Feb 28;12(3):328. doi: 10.3390/brainsci12030328

Table 1.

Autoantibodies associated with autoimmune CA (compiled from [52,53,54,55]).

Autoantigen Clinical Presentation Association with Cancer
AP3B2 CA, peripheral neuropathy Unclear
Ca/ARHGAP26 CA Rare
CARP VIII CA Breast cancer, ovarian cancer, colorectal cancer, SCLC
Caspr2 CA, LE, Morvan syndrome SCLC, thymoma
CV2/CRMP5 CA SCLC, thymoma
GAD65 LE, CA SCLC, neuroendocrine tumors, thymoma
GFAP CA Thymoma, ovarian, prostate, breast cancer
GluRdelta 2 CA, LE Unclear
GlyR CA, encephalitis Thymoma, breast cancer, Hodgkin’s lymphoma, SCLC
Homer3 CA, encephalitis SCLC
Hu CA, LE SCLC
IgLON5 CA None
ITPR1 CA, encephalitis, Breast cancer
Yo CA Breast, ovarian cancer
KLHL11 Brainstem syndrome, CA Testicular cancer
LGl1 CA, encephalitis Thymoma, neuroendocrine tumors
Ma2 LE, CA, brainstem encephalitis Testis and lung cancer
mGluR1 CA Hodgkin’s lymphoma
mGluR2 CA unclear
Neuro chondrin CA None
PCA-2 Limbic/brainstem encephalitis, LEMS, CA SCLC
Ri CA Breast cancer
Septin 5 CA None
SEZ6L2 CA Unclear
TG 2, 6 Gluten ataxia None
Tr/DNER CA, LE Hodgkin’s lymphoma
TRIM 46, 9 & 67 CA SCLC
VGCC CA, LEMS SCLC

CA: cerebellar ataxia, LE: limbic encephalitis, LEMS: Lambert–Eaton myasthenic syndrome, SCLC: small-cell lung cancer.