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Effects of various doses of cefoperazone on elastase activity detectable in supernatants of neutrophils incubated in the presence (■) or absence (●) of α1-AT (3.5 μg) under the following conditions: neutrophils, 2 × 105; phorbol myristate acetate, 10 ng/ml; final volume, 175 μl; and incubation time, 60 min. Results are expressed as nanomoles of substrate cleaved per hour by supernatants of neutrophils (mean ± 1 standard error of the mean, n – 4).
