Table 3.

Classification result of leave-one-out cross-validation.

Patient	Sensitivity	Specificity	PPV a.	NPV b.	AUC c.	MCC d.
1	0.91	0.55	0.79	0.77	0.76	0.51
2	-	0.00	0 *	-	-	-
3	-	0.55	0 *	1.00 *	-	-
4	-	0.99	0 *	1.00 *	-	-
6	0.55	0.87	0.42	0.92	0.79	0.38
7	0.66	0.79	0.64	0.81	0.78	0.45
8	-	1.00	0 *	1.00 *
9	0.95	0.67	0.05	1.00	0.84	0.18
10	0.85	0.88	0.30	0.99	0.89	0.46
11	0.91	0.72	0.98	0.40	0.89	0.49
Mean	0.81	0.70	0.53	0.82	0.83	0.41

^a—PPV: Positive predictive value; ^b—NPV: Negative predictive value; ^c—AUC: Area under the curve; ^d—MCC: Matthew’s correlation coefficient; * Samples without tumor tissue. PPV and NPV were not included in calculation of the mean.