IOERT	intraoperative radiation with electrons
HWBI	hypofractionated whole breast irradiation
BCS	breast conserving surgery
CO	cosmetic outcome
IBR	in breast recurrence
DCIS	ductal carcinoma in situ
RCTs	randomized controlled trials
HIOB	hypofractionated whole breast irradiation preceded by an intraoperative tumorbed boost with electrons
SQRT	sequential ratio test
FUP	follow-up
WBI	whole breast irradiation
RNI	regional node irradiation
PTV	Planning Target Volume
DFS	disease free survival
MFS	metastases free survival
DSS	disease specific survival
OS	overall survival
LC	overall local control
LRC	locoregional control
OPS	oncoplastic surgery
IMRT	intensity modulated radiotherapy
V20	tissue volume which receives 20 Gy or more
QA	quality assurance
ISIORT	International Society of Intraoperative Radiotherapy
CI	confidence interval
itt	intention to treat
pp	per protocol
ET	endocrine therapy
CTX	chemotherapy
H0	Null hypothesis