Skip to main content
. 2022 Mar 12;12(3):439. doi: 10.3390/biom12030439

Figure 1.

Figure 1

Competition ELISA with mimetics. (a) Concentration-dependent reduction of antibody 324 binding to substrate-coated L1-Fc by anagrelide, 2-hydroxy-5-fluoropyrimidine and mestranol. Tegaserod served as negative control. Compounds were incubated with antibody 324 and then tested for binding to substrate-coated mouse L1-Fc. Antibody binding to L1-Fc without compounds was set to 1 for absorbance/OD. Significance of differences between mimetics and tegaserod was determined by one-way ANOVA with Tukey’s post hoc test. * p < 0.05, # p < 0.01. The small error bars show mean ± SEM. (b) Chemical structure of mimetics and tegaserod.