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Doxorubicin enhances chemoresistance in osteosarcoma cells. (A) Schematic of MG63/DOX and 143B/DOX cell preparation. (B) MG63/DOX and 143B/DOX cell viability after treatment with doxorubicin. Cells were treated with various concentrations of doxorubicin for 4 days, and then the MTS assay was performed to analyze cell viability. The data represent the means ± SD. * p < 0.05 and ** p < 0.01 vs. their parental cells.
