Table A6.

Adverse event rates from ZUMA-2.

	Incidence
Adverse Events	Brexucabtagene Autoleucel (%) (se)	BSC (%) (se)
Cytokine release syndrome (CRS) Grade ≥2	62 (6)	0 (0)
Pyrexia	13 (4)	0 (0)
Anemia	50 (6)	0 (0)
Platelet count decreased	38 (6)	0 (0)
Hypotension	22 (5)	0 (0)
Neutrophil count decreased	50 (6)	0 (0)
White blood cell count decreased	40 (6)	0 (0)
Hypoxia	21 (5)	0 (0)
Hypophosphatemia	22 (5)	0 (0)
Neutropenia	34 (6)	0 (0)
Hyponatremia	10 (4)	0 (0)
ALT increased	9 (3)	0 (0)
Encephalopathy	19 (5)	0 (0)
Hypokalemia	7 (3)	0 (0)
Hypocalcemia	6 (3)	0 (0)
Thrombocytopenia	16 (4)	0 (0)
AST increased	10 (4)	0 (0)
Confusional state	12 (4)	0 (0)
Hyperglycemia	6 (3)	0 (0)
Hypertension	13 (4)	0 (0)
Acute Kidney Injury	7 (3)	0 (0)
Leukopenia	13 (4)	0 (0)
Lymphocyte count decreased	9 (3)	0 (0)
Pneumonia	9 (3)	0 (0)
Respiratory Failure	6 (3)	0 (0)
Sepsis	6 (3)	0 (0)

Abbreviations: ALT: alanine aminotransferase; AST aspartate aminotransferase; BSC, best supportive care; SE, standard error.