Table 1. Characteristics of the patients with sepsis.
| Variables | 30-day mortality, n = 911 1 | 30-day survival, n = 1146 0 | P |
|---|---|---|---|
| Age, years | 70[59,81] | 66[54,79] | <0.001 |
| Female, n (%) | 418 (45.88) | 519 (45.29) | 0.788 |
| First care unit, n (%) | 0.035 | ||
| MICU | 294 (32.34) | 398(34.88) | |
| MICU/SICU | 254 (27.94) | 342 (29.97) | |
| SICU | 216 (23.76) | 263 (23.05) | |
| Others | 145 (15,95) | 138 (12.09) | |
| Mechanical Ventilation, n (%) | 247[27.11] | 232[20.24] | <0.001 |
| Comorbidities, n (%) | |||
| Hypertension, n (%) | 106 (11.64) | 193 (16.94) | <0.001 |
| COPD, n (%) | 91 (9.99) | 93 (8.12) | 0.139 |
| Diabetes, n (%) | 46 (5.05) | 59 (5.15) | <0.001 |
| Respiratory failure, n (%) | 374 (41.05) | 309 (26.96) | 0.014 |
| CHF, n (%) | 42 (4.61) | 30 (2.62) | <0.001 |
| Vital signs | |||
| SBP, mmHg | 113.41[105.0,119.2] | 116.3[110.3,119.5] | <0.001 |
| DBP, mmHg | 57.0[51.0,60.3] | 58.4[55.8,61.7] | <0.001 |
| Heart rate, bmp | 94.0[76.0,120.0] | 94.0[71.0,120.0] | 0.093 |
| MAP, mmHg | 72.0[63.0,79.5] | 76.8[70.0,80.0] | <0.001 |
| Laboratory parameters | |||
| Albumin, g/dl | 3.0[2.5,3.6] | 3.2[2.7,3.7] | <0.001 |
| White blood cell,109/L | 14.2[10.8,17.9] | 14.2[11.3,18.0] | 0.507 |
| Hematocrit,% | 35.0[30.0.39.9] | 35,9[31.0,40.8] | <0.001 |
| Platelet,109/L | 153.0[91.0.230.0] | 181.0[125.0,255.0] | <0.001 |
| Bilirubin, mg/dL | 1.3[0.6,3.1] | 0.9[0.4,2.8] | <0.001 |
| Hemoglobin, g/dL | 9.6[9.4,9.9] | 9.6[9.5,9.8] | 0.037 |
| RDW,% | 14.6[13.6,16.2] | 13.9[13.0,15.1] | <0.001 |
| Scr, mg/dl | 1.6[1.0,2.6] | 1.3[0.6,2.1] | <0.001 |
| Lactate, mmol/L | 2.5[1.6,4.6] | 1.9[1.3,2.8] | <0.001 |
| Sodium, mEq/L | 138.0[134.0,142.0] | 139[141.0,135.0] | 0.186 |
| Potassium, mEq/L | 4.2[3.7,4.8] | 4.0[3.6,4.5] | <0.001 |
| Severity scores | |||
| SOFA | 6.0[3.0,9.0] | 4.0[3.0,6.0] | <0.001 |
| SAPSII | 52.0[42.0,63.0] | 42.0[33.0,52.0] | <0.001 |
*Data are expressed as median (IQR), or n (%). Analysis of variance (or the Kruskal-Wallis test) and Chi-square (or Fisher’s exact) tests were used for comparisons among groups. Statistical significance (P<0.05).
ICU, intensive care unit; SICU, Surgical Intensive Care Unit; MICU, Medicine Intensive Care Unit; COPD, Chronic obstructive pulmonary disease; CHF, Congestive heart failure; SBP, Systolic blood pressure; DBP, Diastolic blood pressure; MAP, mean arterial pressure; RDW, Red blood cell distribution width; Scr, Serum creatinine; SOFA, Sequential Organ Failure Assessment; SAPSII, Simplified Acute Physiology Scores II.