Table 3.
Results of tests in 62 premenopausal women with newly diagnosed Graves disease (at inclusion) and 54 matched controls
| Comparison of patients and controls at inclusion | |||||||
|---|---|---|---|---|---|---|---|
| Patients at inclusion | Controls at inclusion | ||||||
| No. | Mean | SD | No. | Mean | SD | P | |
| Trail Making Test A | 62 | 29.3 | 11.8 | 54 | 27.2 | 8.3 | .284 |
| Trail Making Test B | 62 | 71.5 | 26.1 | 54 | 62.4 | 21.8 | .047 |
| Trail Making Test C | 61 | 66.8 | 24.8 | 54 | 58.8 | 24.3 | .085 |
| Trail Making Test D | 61 | 116.0 | 40.9 | 54 | 105.1 | 37.5 | .140 |
| Digit Symbol Coding | 62 | 77.1 | 13.8 | 54 | 82.1 | 12.7 | .044 |
| Digit Span | 62 | 15.3 | 3.4 | 54 | 15.0 | 3.4 | .620 |
| F-A-Sa | 62 | 41.0 | 11.6 | 54 | 43.8 | 12.9 | .215 |
| Reading speed | 61 | 3.1 | 0.9 | 54 | 3.1 | 0.8 | .920 |
| Comparison of patients at 15 mo and controls at inclusion | |||||||
| Patients at 15 mo | Controls at inclusion | ||||||
| No. | Mean | SD | No. | Mean | SD | P | |
| Trail Making Test A | 46 | 23.9 | 8.6 | 54 | 27.2 | 8.3 | .050 |
| Trail Making Test B | 46 | 59.5 | 24.6 | 54 | 62.4 | 21.8 | .533 |
| Trail Making Test C | 46 | 57.9 | 21.7 | 54 | 58.8 | 24.3 | .853 |
| Trail Making Test D | 46 | 98.9 | 38.5 | 54 | 105.1 | 37.5 | .414 |
| Digit Symbol Coding | 46 | 80.9 | 16.3 | 54 | 82.1 | 12.7 | .691 |
| Digit Span | 46 | 15.3 | 3.5 | 54 | 15.0 | 3.4 | .644 |
| F-A-Sa | 46 | 46.6 | 11.0 | 54 | 43.8 | 12.9 | .252 |
| Reading speed | 45 | 3.1 | 0.9 | 54 | 3.1 | 0.8 | .862 |
| Comparison of patients at inclusion and at 15 mo | |||||||
| Patients at inclusion | Patients at 15 mo | ||||||
| No. | Mean | SD | No. | Mean | SD | P | |
| Trail Making Test A | 45 | 28.4 | 12.2 | 45 | 23.9 | 8.7 | 9.0e-04 |
| Trail Making Test B | 45 | 67.8 | 25.3 | 45 | 60.2 | 24.5 | .012 |
| Trail Making Test C | 44 | 62.8 | 21.5 | 44 | 56.7 | 19.6 | .013 |
| Trail Making Test D | 44 | 109.8 | 36.9 | 44 | 97.6 | 37.7 | .013 |
| Digit Symbol Coding | 45 | 77.8 | 13.3 | 45 | 80.5 | 16.2 | .027 |
| Digit Span | 45 | 15.8 | 3.3 | 45 | 15.2 | 3.5 | .227 |
| F-A-Sa | 45 | 43.3 | 10.8 | 45 | 46.7 | 11.1 | .006 |
| Reading speed | 44 | 3.1 | 0.9 | 44 | 3.1 | 0.9 | .600 |
Data are presented as mean and SD. Comparisons between controls and patients are made with t test and between patients at inclusion and at 15 months with paired t test. P values less than .05 are shown in bold.
a F-A-S is a test that measures the total number of words that start with F, A, and S that the test taker can produce in 1 minute.