Table 4.

Volumes of amygdalae and hippocampi in premenopausal women with newly diagnosed Graves disease at inclusion (N = 62) and matched controls (N = 56) at inclusion

	Mean ± SD ICV-normalized volume, mm3
	Patients at inclusion (N = 62)	Controls at inclusion (N = 56)	Difference in mean, mm3	P a
Left amygdala	1135.2 ± 148.4	1266.5 ± 140.3	–131.3	2.8e-6
Right amygdala	994.1 ± 161.5	1146.1 ± 114.9	–152.0	5.0e-8
Left hippocampus	1681.7 ± 160.7	1759.9 ± 177.2	–78.3	.013
Right hippocampus	1799.0 ± 193.7	1889.6 ± 176.8	–90.6	.009

Segmentation was performed with the MAPER (multiatlas propagation with enhanced registration) automatic method. Intracranial volume (ICV)-normalized volumes were used. P values less than .05 are shown in bold.

^a Unpaired t test.