Table 1.
Demographic and baseline variables.
|
± DS
.... |
Total
n = 154 |
NSG
n = 129 |
NFG
n = 25 |
p -Value |
|
Gestational age Birth weight Temperature at admission Apgar score at 1 min Apgar score at 5 min |
29.79 ± 2.00 | 30.09 ± 1.79 | 28.22 ± 2.33 | 0.001 |
| 1185 (960–1410) | 1200 (975–1420) | 1000 (860–1245) | 0.003 | |
| 35.86 ± 0.64 | 35.85 ± 0.61 | 35.92 ± 0.82 | 0.616 | |
| 6.97 ± 1.27 | 6.95 ± 1.18 | 7.04 ± 1.70 | 0.805 | |
| 8.29 ± 0.97 | 8.25 ± 0.93 | 8.48 ± 1.12 | 0.280 | |
| Maximum FiO2 during DR stabilization | 36.41 ± 15.39 | 31.61 ± 6.52 | 52.56 ± 23.79 | <0.001 |
| Age at surfactant administration (hours) n = 62 | 5.24 ± 9.16 | 6.27 ± 11.25 | 3.72 ± 4.43 | 0.287 |
| FiO2 before surfactant administration n = 62 | 33.49 ± 7.80 | 31.72 ± 6.08 | 36.33 ± 9.47 | 0.077 |
| FiO2 after surfactant n = 62 | 27.67 ± 9.41 | 24.35 ± 5.01 | 33.52 ± 12.27 | 0.003 |
| FiO2 decrease after surfactant n = 62 | 5.47 ± 7.37 | 7.13 ± 4.73 | 2.64 ± 10 | 0.097 |
| n (%) |
Total
n = 154 |
NSG
n = 129 |
NFG
n = 25 |
p -Value |
| GA ≤ 28 | 48 (31,2) | 32 (24,8) | 16 (64) | <0.001 |
| IVF | 44 (28.6) | 35 (27.1) | 9 (36) | 0.468 |
| PIH | 41 (26.6) | 34 (26.4) | 7 (28) | 1 |
| Female infant | 76 (49.4) | 66 (51.2) | 10 (40) | 0.384 |
| ANS | 153 (99.4) | 128 (99.2) | 25 (100) | 1 |
| Multiple birth | 59 (38.3) | 47 (36.4) | 12 (48) | 0.369 |
| Cesarean section | 120 (77.9) | 101 (78.3) | 19 (76) | 1 |
| SGA | 17 (11) | 14 (10,9) | 3 (12) | 0.867 |
| Chorioamnionitis | 23 (14.9) | 17 (13.2) | 6 (24) | 0.220 |
| Surfactant | 62 (40.3) | 37 (28.7) | 25 (100) | <0.001 |
| NIPPV as initial support | 52 (33.8) | 38 (29.5) | 14 (56) | 0.032 |
| Caffeine | 145 (94.2) | 126 (97.7) | 19 (76) | <0.001 |
Bolded values denote p < 0.05; Quantitative variables are presented as mean ± standard deviation (SD) for normally distributed variables and as median (interquartilic range) for non-normal ones. NSG, non-invasive success group; NFG, non-invasive failure group; FiO2, fraction of inspired oxygen; DR, delivery room; IVF, in vitro fertilization; PIH, pregnancy-induced hypertension; ANS, antenatal steroids; SGA, small for gestational age; NIPPV, non-invasive intermittent positive ventilation.