Table 2.
Outcome variables.
| n (%) |
Total
n = 154 |
NSG
n = 129 |
NFG
n = 25 |
p-Value |
| Died | 10 (6.5) | 0 (0) | 10 (40) | <0.001 |
| BPD | 24 (15.6) | 16 (12.4) | 8 (32) | 0.022 |
| BPD moderate-to-severe | 7 (4.5) | 3 (2.3) | 4 (16) | 0.014 |
| Survival without BPD | 120 (77.9) | 113 (87.6) | 7 (28) | <0.001 |
| Survival without moderate-to-severe BPD | 137 (89) | 126 (97.7) | 11 (44) | <0.001 |
| Home supplementary oxygen | 10 (6.5) | 1 (0.8) | 9 (36) | <0.001 |
| IMV during admission | 35 (22.7) | 11 (8.5) | 25 (100) | <0.001 |
| Steroids for BPD | 11 (7.1) | 4 (3.1) | 7 (28) | <0.001 |
| Pneumothorax | 5 (3.2) | 1 (0.8) | 4 (16) | 0.002 |
| IVH > II | 11 (7.1) | 4 (3.1) | 7 (28) | <0.001 |
| PVL | 6 (3.9) | 4 (3.1) | 2 (8) | 0.250 |
| ROP > II | 5 (3.8) | 3 (2.5) | 2 (13.3) | 0.097 |
| PDA | 22 (14.3) | 17 (13.2) | 5 (20) | 0.532 |
| Surgery for PDA | 6 (3.9) | 4 (3.1) | 2 (8) | 0.251 |
| Ibuprofen for PDA | 13 (8.4) | 10 (7.8) | 3 (12) | 0.445 |
| NEC (≥ stage 2) | 7 (4.5) | 5 (3.9) | 2 (8) | 0.610 |
| Isolated intestinal perforation | 3 (1.9) | 0 (0) | 3 (12) | 0.004 |
| Culture positive sepsis | 46 (29.9) | 38 (29.5) | 8 (32) | 0.810 |
| ± DS |
Total
n = 154 |
NSG
n = 129 |
NFG
n = 25 |
p-Value |
| Weight at discharge | 2256.21 ± 436.36 | 2313.13 ± 319.23 | 1925 ± 774.64 | 0.033 |
| Weight Z-Score at discharge | −1.49 ± 1.15 | −1.50 ± 1.19 | −1.38 ± 0.88 | 0.652 |
| Age at first intubation (hours) n = 35 | 42.85 ± 83.35 | 210 ± 124.52 | 13.78 ± 11.54 | 0.051 |
| Duration of hospitalization (days) * | 57.51 ± 63.57 | 56.91 ± 66.84 | 62.60 ± 21.35 | 0.744 |
| NICU length of stay (days) * | 21.79 ± 14.34 | 20.84 ± 13.45 | 29.80 ± 19.20 | 0.022 |
| MV (hours) * | 96 (34–216) | 72(36–168) | 96 (31–306) | 0.221 |
| NIV (hours) * | 96 (48v168) | 96 (48–168) | 72 (48–216) | 0.210 |
| Supplemental oxygen (hours) * | 192 (68–648) | 192 (72–564) | 120 (65–972) | 0.009 |
| Number of doses of surfactant | 1 (1–1.25) | 1 (1–1) | 1 (1–2) | 0.003 |
Bolded values denote p < 0.05; * Only among survivors; Quantitative variables are presented as mean ± standard deviation (SD) for normally distributed variables and as median (interquartilic range) for non-normal ones. BPD, bronchopulmonary dysplasia; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia; ROP, retinopathy of prematurity; PDA, patent ductus arteriosus; NEC, necrotizing enterocolitis; NICU, neonatal intensive care unit; MV, mechanical ventilation; NIV, non-invasive ventilation.