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Baseline predictors of dementia in Parkinson disease within 10 years. Six early predictors (A–F) of PDD. The Kaplan–Meier graphs show the effect of baseline predictors above and below specified cut-offs on PDD risk. All cut-offs were made at the highest Youden Index. NfL, neurofilament light chain protein; Aβ42, amyloid-β 42; DAT, dopamine transporter; UPDRS, Unified Parkinson’s Disease Rating Scale. P-value < 0.001 (log rank) for all predictors, A through F).
