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. 2022 Mar 24;17(3):e0265770. doi: 10.1371/journal.pone.0265770

Table 4. Effects of the fluid bolus.

Parameter Baseline Difference from baseline after bolus, median (IQR) Difference from baseline after 1 hour, median (IQR)
MAP (mmHg) 69.7 (64.2–78.0) 4.4 (-2.3–9.7) 2.5 (-2.2–10.0)
N baseline = 77
N after bolus = 75
N after 1 hour = 75
UO (ml/h) 60.0 (25.0–150.0) N/A -15.0 (-60.0–15.0)
N baseline = 73
N after 1 hour = 71
HR (bpm) 92.9 (79.0–111.0) -1.0 (-5.4–1.5) -0.2 (-5.2–2.9)
N baseline = 77
N after bolus = 76
N after 1 hour = 77
CI (L/min/m2) 2.68 (2.14–3.10) 0.00 (-0.13–0.09) 0.17 (-0.12–0.37)
N baseline = 24
N after bolus = 23
N after 1 hour = 22
Lactate (mmol/L) 1.3 (0.9–1.9) 0.0 (-0.3–0.1) -0.1 (-0.3–0.2)
N baseline = 68
N after bolus = 28
N after 1 hour = 48
CVP (mmHg) 10.3 (8.0–12.9) 3.1 (1.5–5.2) 0.5 (-1.6–1.7)
N baseline = 23
N after bolus = 21
N after 1 hour = 23
ScvO2 (%) 65.0 (62.2–71.1) Too small sample size Too small sample size
N baseline = 4
N after bolus = 3
N after 1 hour = 3

Values are presented as median with (IQR).

MAP = Mean arterial pressure. UO = Urine output. HR = Heart rate. CI = Cardiac index. CVP = Central venous pressure. ScvO2 = Central venous oxygen saturation. N/A = Not applicable.