Table A6.
Statistical analysis of neck EMG during sleep.
| ♀ hTau and WT d14 and d45 Total N = 15 |
♀ hTau and WT d14 Total N = 20 |
♂ hTau d14 and d45 Total N = 7 |
|
|---|---|---|---|
| ANOVA factor or interaction | p value | p value | p value |
|
Ab (Pt-IgG vs. Ctrl-IgG) |
0.848 | 0.378 | 0.458 |
| Mouse Strain
(hTau vs. WT) |
0.415 | 0.024 * | N/A |
| Ab x Strain | 0.341 | 0.344 | N/A |
|
SS (NREM sleep vs. REM sleep) |
<0.001 * | <0.001 * | 0.005 * |
| Ab x SS | 0.326 | 0.841 | 0.682 |
| Strain x SS | 0.029 * | 0.179 | N/A |
| Ab x Strain x SS | 0.145 | 0.023 * | N/A |
| Time (d14 vs. d45) | 0.133 | N/A | 0.205 |
| Ab x Time | 0.552 | N/A | 0.589 |
| Strain x Time | 0.007 * | N/A | N/A |
| Ab x Strain x Time | 0.663 | N/A | N/A |
| Time x SS | 0.019 * | N/A | 0.169 |
| Ab x Time x SS | 0.352 | N/A | 0.186 |
| Time x SS x Strain | 0.001 * | N/A | N/A |
| Ab x Time x SS x Strain | 0.903 | N/A | N/A |
ANOVA: analysis of variance, with “x” indicating interactions. Ab: antibody. SS: sleep state. N/A: not applicable. ♀ and ♂: female and male, respectively. The meaning of the other abbreviations is the same as in the main manuscript. *: statistically significant (P < 0.05). Experiments were performed on 4 ♀ WT with Pt-IgG at d14 and d45; 4 ♀ WT with Ctrl-IgG at d14, of which 3 also at d45; 7 ♀ hTau with Pt-IgG at d14, of which 4 also at d45; 5 ♀ hTau with Ctrl-IgG at d14, of which 4 also at d45; 4 ♂ hTau with Pt-IgG at d14 and d45; 3 ♂ hTau with Ctrl-IgG at d14 and d45.