This 89-year-old patient (A) showed buccal bone loss, assessed using an intraoral X-ray (B), and a gingival fistula at the study implant D13 (C). The visual plaque index measured 1/3 at the beginning of the study, with a probing depth of 4 mm. The aMMP-8 value in the peri-implant sulcular fluid was 78.18 ng/mL at the beginning of the study (D). After two weeks of Lumoral® dual-light aPDT treatment repeated once a day, the aMMP-value was 51.70 (D), after which the Lumoral® treatment was repeated twice a day for the next two weeks. At four weeks, the aMMP-8 was 23.76 ng/mL, and the visual plaque index measured 0/3. In this patient, bleeding on probing was measured positive though the whole study period, and no change was observed in the probing depth.