Figure A1.

Visualization of the probability density distributions used to sample T2 relaxation times and signal intensities (S₀) for the synthetic dataset. The T2 relaxation times were sampled from a log-normal distribution with $z=\frac{x-5}{70}$ and probability density function $f\left(z\right) ~\frac{1}{70}\frac{1}{0.66x \sqrt{2\pi }} \exp \left(-\frac{\mathit{ln}{\left(z\right)}^2}{2 · {0.66}^2}\right)$. The signal intensities followed a customized probability density function $f\left(x\right)$, which was defined as: $f\left(x\right)=0$ for $x<0$; $f\left(x\right)=\frac{1}{1000}$ for $0\le x\le 500$; $f\left(x\right)=\frac{1}{1000}\exp \left(1-\frac{x}{500}\right)$ for $x>500$.