Table 1.

Sex-stratified results for variants identified in joint and sex specific analyses of genotyped rare variants in UK Biobank

Variant	rsID	P sex interaction	P Women	P Men	β Women	β Men	SE Women	SE Men
PLIN1 p.L90P	rs139271800	4.07 × 10–3	1.90 × 10–13	4.50 × 10–3	–0.273	–0.126	0.039	0.042
PDE3B p.R783X	rs150090666	5.66 × 10–5	1.00 × 10–19	4.10 × 10–2	–0.392	–0.102	0.042	0.048
ACVR1C p.I195T	rs56188432	0.36 × 10–1	1.10 × 10–8	3.40 × 10–4	–0.16	–0.109	0.028	0.032
CALCRL p.L87P	rs61739909	4.30 × 10–3	4.30 × 10–13	2.50 × 10–3	–0.171	–0.082	0.024	0.026
ABHD15 p.G147D	rs141385558	4.53 × 10–3	3.40 × 10–10	3.80 × 10–2	0.168	0.057	0.026	0.029
PYGM p.R50X	rs116987552	0.36 × 10–1	2.90 × 10–4	5.40 × 10–5	0.079	0.095	0.021	0.024
PLCB3 p.V806I	rs145502455	2.34 × 10–2	1.60 × 10–10	0.20 × 10–1	0.126	0.029	0.021	0.024
FNIP1 p.R518Q	rs115209326	6.09 × 10–4	4.80 × 10–9	0.84 × 10–1	–0.128	–0.003	0.023	0.026

Unshaded rows present results discovered from the sex-combined analysis, and gray-shaded rows represent results from variants identified only in the sex-stratified (women) analysis.

Abbreviations: β Men, effect size in men; β Women, effect size in women; P Men, BOLT LMM P value in men; P Women, BOLT LMM P value in women.