Table 1.
Baseline demographic and clinical characteristics of patients undergoing CABG in the SYNTAX trial
| Characteristics | CABG (n = 1466)a |
P-value | |
|---|---|---|---|
| MAG (N = 465) | SAG (N = 1001) | ||
| Age (years) | 62.3 ± 9.7 | 66.5 ± 9.2 | <0.001 |
| Female gender | 64 (13.8) | 224 (22.4) | <0.001 |
| BMI ≥30 (kg/m2) | 144 (31.0) | 310/1000 (31.0) | 0.99 |
| Medically treated diabetes | |||
| Oral medication or insulin | 103 (22.2) | 259 (25.9) | 0.12 |
| Insulin | 38 (8.3) | 102 (10.2) | 0.22 |
| History of nicotine abuse | 319/462 (69.0) | 657/994 (66.1) | 0.27 |
| History of chronic obstructive pulmonary disease | 34 (7.3) | 89 (8.9) | 0.31 |
| Carotid artery disease | 45 (9.7) | 101 (10.1) | 0.81 |
| Peripheral vascular disease | 49 (10.5) | 128 (12.8) | 0.22 |
| Creatinine >200 μmol/l | 6 (1.3) | 21 (2.1) | 0.29 |
| History of myocardial infarction | 128/457 (28.0) | 351/984 (35.7) | 0.004 |
| History of stroke or TIA | 39/464 (8.4) | 94/996 (9.4) | 0.52 |
| Medically treated hypertension (≥130/85 mmHg) | 344/459 (74.9) | 742/990 (74.9) | >0.99 |
| Medically treated hyperlipidaemia | 361/459 (78.6) | 751/985 (76.2) | 0.31 |
| Angina | |||
| Stable | 265 (57.0) | 610 (60.9) | 0.15 |
| Unstable | 119 (25.6) | 256 (25.6) | 0.99 |
| Impaired left ventricular ejection fraction (<50%)b | 74 (15.9) | 265/996 (26.6) | <0.001 |
| EuroSCORE I value | 2.9 ± 2.9 | 4.4 ± 4.9 | <0.001 |
| SYNTAX scorec | 32.2 ± 12.8 | 33.3 ± 13.0 | 0.14 |
| Number of lesionsc | 4.3 ± 1.7 | 4.4 ± 1.8 | 0.80 |
| Left main,d any | 181 (38.9) | 445 (44.5) | 0.046 |
| Three-vessel,d without left main involvement | 284 (61.1) | 556 (55.5) | 0.046 |
Values are shown as mean ± standard deviation or frequencies in percentages and (n) unless otherwise noted.
a
Data are reported according to the as-treated principle based on the randomized and registry as-treated CABG patients.
b
Impaired left ventricular ejection fraction was defined as <50%.
c
Core laboratory assessment.
d
Site reported.
BMI: body mass index; CABG; coronary artery bypass grafting; EuroSCORE: European System for Cardiac Operative Risk Evaluation; MAG: multiple arterial grafts; SAG: single arterial graft; TIA: transient ischaemic attack.