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. 2022 Mar 24;16:100354. doi: 10.1016/j.lanepe.2022.100354

Table 3.

Differences in acute COVID-19 symptom prevalence between participants reporting mild symptom burden and severe symptom burden.

SARS-CoV-2 positive population
Total population (n = 6630) Self-reported mild symptom burden (n = 3795) Self-reported severe symptom burden (n = 594) p-valuea
Fever, n (%) 1768 (26.7) 1383 (36.4) 385 (64.8) <0.0001
Cold, n (%) 1939 (29.3) 1594 (42.0) 345 (58.1) <0.0001
Sore throat, n (%) 2063 (31.1) 1677 (44.2) 386 (65.0) <0.0001
Cough, n (%) 2093 (31.6) 1711 (45.1) 382 (64.3) <0.0001
Stomach aches, n (%) 568 (8.6) 390 (10.3) 178 (30.0) <0.0001
Rashes, n (%) 105 (1.6) 72 (1.9) 33 (5.6) <0.0001
Trouble breathing, n (%) 1129 (17.0) 787 (20.7) 342 (57.6) <0.0001
Reduced sense of smell, n (%) 2398 (36.2) 2002 (52.8) 396 (66.7) <0.0001
Reduced sense of taste, n (%) 2062 (31.1) 1689 (44.5) 373 (62.8) <0.0001
Chest pain, n (%) 393 (5.9) 232 (6.1) 161 (27.1) <0.0001
Headaches, n (%) 2597 (39.2) 2118 (55.8) 479 (80.6) <0.0001
Vomiting, n (%) 139 (2.1) 76 (2.0) 63 (10.6) <0.0001
Diarrhoea, n (%) 281 (4.2) 197 (5.2) 84 (14.1) <0.0001
Muscle pain, n (%) 1234 (18.6) 903 (23.8) 331 (55.7) <0.0001
Joint pain, n (%) 748 (11.3) 522 (13.8) 226 (38.1) <0.0001
Pain, n (%) 448 (6.8) 250 (6.6) 198 (33.3) <0.0001
Feeling unwell, n (%) 1652 (24.9) 1252 (33.0) 400 (67.3) <0.0001
Number of symptoms (median, interquartile range) 2 (0–5) 4 (2–6) 8 (5–11) <0.0001
a

Differences in prevalence of symptom between participants reporting mild and severe symptom burden tested using two-sided χ2-tests.