Table 4.

Factors associated with reporting number of symptoms in the upper quartile and severe acute symptom burden.

	Reporting number of symptoms in the upper quartile (≥6)	p-value	Self-reported severe symptom burden	p-value
	OR (95%CI)a		OR (95%CI)a
Age
15 years	1.0 (ref)		1.00 (ref)
16 years	1.08 (0.88;1.31)	0.4755	1.14 (0.83;1.57)	0.4163
17 years	1.28 (1.06;1.55)	0.0098	1.47 (1.09;1.98)	0.0110
18 years	1.47 (1.23;1.76)	<0.0001	1.61 (1.21;2.14)	0.0011
+18	1.40 (1.13;1.74)	0.0022	1.98 (1.43;2.73)	<0.0001
Sex
Female vs. male	1.88 (1.67;2.12)	<0.0001	1.41 (1.18;1.68)	0.0002
Asthma
Yes vs. No	1.39 (1.14;1.70)	0.0012	1.52 (1.15;2.00)	0.0034
Allergy
Yes vs. no	1.23 (1.07;1.41)	0.0042	1.64 (1.35;1.99)	<0.0001
Eczema
Yes vs. no	1.37 (1.09;1.72)	0.0073	1.57 (1.15;2.15)	0.0049
OCD/anxiety/depression
Yes vs. no	1.67 (1.34;2.09)	<0.0001	1.74 (1.28;2.36)	0.0004
Epstein-Barr virus
Yes vs. no	1.48 (1.00;2.19)	0.0500	2.26 (1.40;3.63)	0.0008

^aLogistic regression model with reporting number of symptoms in the upper quartile (≥6) and reporting severe symptom burden as outcomes. Each covariate is included separately in the model but adjusted for sex and age.