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. 2022 Mar 17;2022:1971559. doi: 10.1155/2022/1971559

Figure 1.

Figure 1

miR-106b-5p is frequently upregulated in HCC tissues and cell lines. (a) A heatmap showing differential expression of miRNAs in 7 paired HCC tissues by miRNA microarray. (b) miR-106b-5p expression in HCC and adjacent para-tumor tissues by qPCR (n = 90). (c) miR-106b-5p expression in HCC (n = 371) and adjacent para-tumor tissues (n = 50) from TCGA database. (d) miR-106b-5p expression in HCC and nontumor tissues by FISH. Scale bar represents 50 μm. (e) Overall survival rate in HCC patients with the low and high miR-106b-5p expression groups. (f) qPCR analysis of miR-106b-5p in HCC cell lines and L02 cells. Data were analyzed using formula 2−(ΔΔCT). Data represent mean ± SD for (b) and (c).  ∗P < 0.05 and ∗∗∗P < 0.001.