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. 2022 Mar 25;39(2):110680. doi: 10.1016/j.celrep.2022.110680

Figure 3.

Figure 3

Antibody response of convalescent and naive octogenarians after two vaccine doses

(A and B) Five nuns (median age 86 years old) with underlying co-morbidities received two doses of the BNT162b2 vaccine 10 months after recovering from COVID-19.

(C and D) Five naive nuns (median age 73 years old) with no underlying co-morbidities received two doses of the BNT162b2 vaccine.

(E) Plasma IgG antibody binding to the SARS-CoV-2 RBD (spike) from different variants and the N protein (naive two doses, n = 5; previously infected two doses, n = 5).

(F) Comparison of antibody titers between two naive groups. p values are from two-way ANOVA with Sidak’s multiple comparisons test. The individual data are listed in Table S2. Colors in dot plots were matched to ones in timetable in (A) and (C) (naive two doses [median 73 years], n = 5; naive two doses [median 58 years], n = 14).