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. 2021 Dec 2;40(3):739–746. doi: 10.1007/s00345-021-03900-5

Fig. 2.

Fig. 2

A Association Copy Number Variations (CNV) of thioredoxin 1 with clinicopathological features in The Cancer Genome Atlas project. Demonstrates the association of copy number variation with clinicopathological features. Black barrs (< 0) represent genome losses while red barrs (≥  0) represent diploid and gain variations in the genome. There was a clear correlation of genome losses with advanced clinicopathological features. B Overall and Cancer Specific Survival outcome according to copy number variations. Represents the association of copy number variations with overall survival, disease-specific survival and progression free intervall. Genome losses were associated with significantly worse survival outcome