Table 1.

(A) Univariable association of compartment-specific Trx1 expression and cancer-specific survival; (B) Multivariable association of compartment-specific Trx1 expression, Stage, Size, Grade and Necrosis Score (SSIGN) with cancer-specific survival

A
Variable	Hazard ratio	95% CI lower bound	95% CI upper bound	p value
No Trx1	Reference
Nuclear Trx1	1.82	0.68	4.97	0.234
Cytoplasmic TrX1	3.13	1.21	8.04	0.018
Nuclear + Cytoplasmic TrX1	1.37	0.51	3.66	0.536

B
Variable	Hazard ratio	95% CI lower bound	95% CI upper bound	p value
SSIGN 0–2 reference	–	–	–	–
SSIGN 3–4	1.43	0.61	3.03	0.407
SSIGN 5–6	2.77	1.13	6.18	0.013
SSIGN 7–9	4.97	1.86	10.35	< 0.001
SSIGN > 10	13.87	6.36	34.10	< 0.001
Trx1 continous	1.00	0.02	1.01	0.371