Table 1.

Summary of top six independent SNP-cytokine loci

Loci	SNPs	Chr	Base pair	Cytokines	Stimulation	p value	Causal genes
1	rs12169244	22	47,558,596	IL-1b	S. enteritidis	1.74 × 10−8	TBC1D22Aa
2	rs9563018	13	51,656,046	IL-1b	M. tuberculosis	7.81 × 10−8	LINC0037,aGUCY1B2b
3	rs4474665	16	17,498,563	IFN-g	S. enteritidis	7.99 × 10−8	XYLT1a
4	rs74115411	1	153,331,776	IL-6	S. aureus	8.90 × 10−8	S100A9a
5	rs11829172	12	98,579,287	IL-1b	S. aureus	9.63 × 10−8	MIR4303a
6	rs10483241	12	48,630,139	IFN-g	C. albicans	9.71 × 10−8	MIR4303a

^aThe gene in closest proximity to the cytokine QTL SNPs.

^bExpression of this gene shows association with cytokine QTL SNP in whole blood.