Figure 4.

Performance comparing MACIE and other functional scores on predicting CAGE promoters and CAGE enhhancers from 1000 Genomes Project phase 3 data

ROC curves comparing the performances of MACIE and other functional scores in discriminating between (A) CAGE-identified promoters and non-promoters and (B) CAGE-identified enhancers and non-enhancers among non-coding variants from 1000 Genomes Project phase 3 data. For CAGE Enhancer predictions, LINSIGHT was excluded because it uses the FANTOM5 enhancer label as one of the genomic features in building the LINSIGHT score.