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. 2022 Feb 24;109(3):446–456. doi: 10.1016/j.ajhg.2022.01.017

Figure 6.

Figure 6

LocusZoom plot for GWAS associations of LDL-C at the APOE locus

The lipid GWAS summary statistics were from the European Network for Genetic and Genomic Epidemiology (ENGAGE) Consortium (n = 58,381).40 The MACIE-protein and MACIE-conserved scores for rs7412 are 0.96 and 0.97, respectively. The MACIE-conserved and MACIE-regulatory scores for rs1065853 are <0.01 and >0.99, respectively. LDL-C, low-density lipoprotein cholesterol.