LocusZoom plot for GWAS associations of LDL-C at the APOE locus
The lipid GWAS summary statistics were from the European Network for Genetic and Genomic Epidemiology (ENGAGE) Consortium (n = 58,381).40 The MACIE-protein and MACIE-conserved scores for rs7412 are 0.96 and 0.97, respectively. The MACIE-conserved and MACIE-regulatory scores for rs1065853 are <0.01 and >0.99, respectively. LDL-C, low-density lipoprotein cholesterol.