Table 4.
Comparison | miRNA | Threshold | Sensitivity% | 95% CI | Specificity% | 95% CI | Likelihood ratio |
---|---|---|---|---|---|---|---|
CMT 0 vs. CMT 1 | miR-26a | > 0.1696 | 91.67 | 74.15 to 98.52 | 74.07 | 55.32 to 86.83 | 3.536 |
miR-142 | > 3.787e-005 | 100 | 86.20 to 100.0 | 81.48 | 63.30 to 91.82 | 5.4 | |
miR-146a | > 1.366e-006 | 100 | 86.20 to 100.0 | 70.37 | 51.52 to 84.15 | 3.375 | |
miR-223 | > 1.509e-005 | 100 | 86.20 to 100.0 | 85.19 | 67.52 to 94.08 | 6.75 | |
CMT 0 vs. CMT > 1 | miR-26a | > 0.9091 | 88.89 | 67.20 to 98.03 | 92.59 | 76.63 to 98.68 | 12 |
miR-142 | > 0.01432 | 100 | 82.41 to 100.0 | 85.19 | 67.52 to 94.08 | 6.75 | |
miR-146a | > 0.09598 | 100 | 82.41 to 100.0 | 88.89 | 71.94 to 96.15 | 9 | |
miR-223 | > 0.01178 | 100 | 82.41 to 100.0 | 85.19 | 67.52 to 94.08 | 6.75 |
Data with the highest combined values of sensitivity and specificity obtained for each miRNA are shown