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Preparation of various Niosome-encapsulated imipenem formulations.
| Formulations | Different compounds of surfactant:cholesterol | Span + tween + cholesterol molar ratio | Span:tween molar ratio | Drug concentration (mg/ml) |
|---|---|---|---|---|
| Different formulations of Niosomal Imipenem | ||||
| F1 | Span 60 + Tween 60 + Cholesterol | 3:3:4 | 50:50 | 1 |
| 25:75 | 1 | |||
| 75:25 | 1 | |||
| F2 | Span 40 + Tween 40 + Cholesterol | 3:3:4 | 50:50 | 1 |
| 25:75 | 1 | |||
| 75:25 | 1 | |||
