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. 2022 Mar 24;8:41. doi: 10.1038/s41523-022-00398-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The higher levels of GLUT1 positive cells are observed at proliferation zones and tumor areas. GLUT1 stained MIN-O tissues at 7-week a–f and 10-week g–l were analyzed for positive cell density m, n and the levels of GLUT1 d–f, j–l. Images were analyzed at proliferation zones a, d, g, j, differentiation zones b, e, h, k and tumor areas (indicated as AdenoCa; c, f, i, l. The color indicates the levels of GLUT1 d–f, j–l as brighter color as higher GLUT1 levels and dark color as lower GLUT1 levels. m, n Graphs show the measurement of GLUT1 positive cell densities (positive percentage) at proliferation zones, differentiation zones and tumor areas in m 7-week and n10-week MIN-O tissues. Bars represent mean value ± standard deviation. Scale bar indicates 100 µm. All images were adjusted to same magnification.