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. 2022 Mar 25;63:8. doi: 10.1186/s40529-022-00339-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Synthesis pathway of amino acids. Red indicates a significant increase in metabolite content in the experimental group, blue represents the metabolite was detected but no significant change, and green indicates a significant decrease in metabolite content in the experimental group. The red boxes represent that the metabolite content is significantly up-regulated in HN65, and the blue boxes represent that the metabolite is detected in HN65 but have no significant change