Table 1.

Endpoints of the PrevHPV study

Dimension/measure	Target population	Data sources	Time frame
Vaccine coverage (main objective)
≥1 dose	Adolescents 11–14 years	Health insurance (SNDS), vaccination centres	M2, M6, M12
2 doses	Adolescents 11–14 years	Health insurance (SNDS), vaccination centres	M2, M6, M12
Knowledge, beliefs, behaviours, practices, intention towards HPV vaccination (secondary objective 1)
Items of the KABP-6C questionnaire	Adolescents, parents and GPs	Self-administered online questionnaires	Before intervention, M2
Efficiency (secondary objective 2)
Incremental cost-effectiveness ratio	Adolescents 11–14 years	Costs of the intervention, Health insurance (SNDS), vaccination centres	M2, M6, M12
Annual cost and health gains of generalising the component(s) at the national level*	Adolescents 11–14 years (whole country)	Costs of the intervention, Health insurance (SNDS), vaccination centres	/
Intervention components’ implementation (secondary objective 3)
Intervention components’ dose and fidelity: activities performed according to the frame of reference for each component, use of tools developed for each component (assessment of the gap between activities/tools planned and activities/ tools really performed/used)	/	Regular activity reports collected on a standardised form during components’ implementation
Reached populations: percentage of target individuals who benefit from (or participate in) activities of each component (assessment of the acceptability of each component)	Adolescents, parents, school staff and GPs	Regular activity reports collected on a standardised form during components’ implementation
Intervention components’ adaptation: components modified to adapt them to the local context/environment of each school/municipality	/	Regular activity reports collected on a standardised form during components’ implementation
Satisfaction of target populations regarding each activity/component and identification of barriers and levers to components’ implementation	Adolescents, parents, schools and vaccination centres’ staff and GPs	Self-administered (paper or online) questionnaires collected at the end of the components’ implementation

*Costs associated with generalising effective component(s) at 1 and 5 years will be compared with the corresponding health gains in terms of size of the vaccinated population (1 and 2 doses).

GPs, general practitioners; HPV, human papillomavirus; KABP-6C, Knowledge, attitude, behaviours, practices and six psychological determinants of vaccination intention (Confidence, Complacency, Constraints, Calculation, Collective responsibility and social Conformism); SNDS, Système National des Données de Santé.