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. 2022 Mar 7;12:763926. doi: 10.3389/fonc.2022.763926

Table 2.

Univariate and multivariate Cox regression for PFS in the population of analysis.

Univariate Cox regression Multivariate Cox regression
n (events) HR 95%CI p-value n (events) HR 95%CI p-value
Gender Male 34 (30) 1 0.9242
Female 6 (6) 1.04 0.43-2.54
Age at treatment initiation Continuous 40 (36) 1.02 1.00-1.05 0.103
<70 22 (20) 1 0.1274 22 (20) 1 0.6909
70 18 (16) 1.69 0.87-3.31 18 (16) 1.16 0.55-2.46
ECOG PS 0 21 (19) 1 0.142 21 (19) 1 0.1001
1 19 (17) 1.64 0.85-3.17 19 (17) 1.86 0.89-3.91
Initial Diagnosis
Primary tumor Stomach 27 (26) 1 0.8953
GEJ/lower esophagus 13 (10) 0.95 0.46-1.98
Histology Well 10 (8) 1 0.2965
Moderately/undifferentiated 25 (25) 1.54 0.69-3.44
Metastasis location
Peritoneum No 31 (28) 1 0.2394
Yes 9 (8) 1.61 0.73-3.57
Lymph nodes No 17 (16) 1 0.8914
Yes 23 (20) 0.96 0.49-1.85
Lung No 32 (29) 1 0.4712
Yes 8 (7) 0.73 0.31-1.71
Liver No 13 (11) 1 0.2355
Yes 27 (25) 1.55 0.75-3.18
Taxanes No 19 (18) 1 0.0418 19 (18) 1 0.033
Yes 21 (18) 0.49 0.25-0.98 21 (18) 0.44 0.21-0.94

Population of analysis: patients with ECOG PS 0 - 1 and synchronous metastasis. CI, Confidence Interval; HR, Hazard Ratio; PS, Performance Status.

Bold text: significant p-value.