Figure 4.

Circ_0078767 regulates the proliferation, migration, and invasion by targeting miR-665 in NSCLC cells. (a, b) The expression level of miR-665 was determined by qRT-PCR. (c) Colony formation assay was used to assess proliferation of transfected A549 and HCC827 cells. (g, h) Transwell assay was used to assess cell migration and invasion. (f, g) Glucose consumption and lactate production were measured to assess glycolysis metabolism using commercial kits. (h, i) The protein expression level of MMP9 and HK2 was tested by western blot analysis. ^∗∗∗P < 0.001.