Figure 6.

GPX3 regulates the proliferation, migration, and invasion by targeting miR-665 in NSCLC cells. (a, b) The protein level of GPX3 was determined by Western blot. (c) Colony formation assay was used to assess proliferation of transfected A549 and HCC827 cells. (d, e) Transwell assay was used to assess cell migration and invasion. (f, g) Glucose consumption and lactate production were measured to assess glycolysis metabolism using commercial kits. (h, i) The protein level of MMP9 and HK2 was detected by Western blot. ^∗∗∗P < 0.001.